Semantic Coherence: IMFINZI (durvalumab) – Signal Evidence & AI Readability

IMFINZI (durvalumab)

(https://imfinzi.com) 📸 Data Snapshot: May 30, 2026
Semantic Coherence — The Lens

Pull the main entities out of the H1, then check whether they actually recur through the body. A page that announces one thing and then talks about another drifts. Headings with no real sentences underneath read as pseudo-substance.

Semantic Coherence Homepage promise vs. Sub-page reality.
18 Impact Weight: 20 / 100
90% Reputation

There is no detectable semantic drift between the homepage and sub-pages. The homepage H1 ‘IMFINZI treats multiple types of cancer’ is systematically supported by dedicated sub-pages for NSCLC, SCLC, and Gastric Cancer, each providing deeper clinical detail. The messaging remains consistent throughout, moving from high-level indications to granular stage-based treatment options without conflicting claims.

Semantic Coherence is read from the heading hierarchy first: what each page announces in its H1 and headings, then whether the body actually delivers on it. Below is the structure the engine mapped, followed by the clean text to check for drift between promise and reality.

🏗️ Semantic Structure — heading hierarchy & page identity (the promise the page makes)
HOMEPAGE Immunotherapy for Certain Cancers – IMFINZI® (durvalumab) (https://imfinzi.com)
Title

Immunotherapy for Certain Cancers – IMFINZI® (durvalumab)

Meta

IMFINZI® (durvalumab) is an immunotherapy approved to treat patients with NSCLC, SCLC, GC/GEJC, uHCC, BTC, MIBC and advanced or recurrent dMMR.

H1 IMFINZI treats multiple types of cancer
H2 SELECT YOUR CANCER TYPE
H2 Select your SCLC stage
H2 ISI
H2 Important Safety Information
H2 What are IMFINZI and IMJUDO?
H2 What are IMFINZI and IMJUDO?
H2 What are IMFINZI and IMJUDO?
H2 Important Safety Information
H2 Important Safety Information
H2 What are IMFINZI and IMJUDO?
H3 What is the most important information I should know about IMFINZI® (durvalumab) and IMJUDO® (tremelimumab-actl)?
H3 Call or see your healthcare provider right away if you develop any new or worsening signs or symptoms, including:
H3 What are the possible side effects of IMFINZI and IMJUDO?
H3 IMFINZI and IMJUDO can cause serious side effects (see above).
H3 What is the most important information I should know about IMFINZI® (durvalumab) and IMJUDO® (tremelimumab-actl)?
H3 What is the most important information I should know about IMFINZI® (durvalumab) and IMJUDO® (tremelimumab-actl)?
HEADER_HEADING_REPEATED_BODY Immunotherapy for Resectable Stage 2A-3B Non-Small Cell Lung Cancer – IMFINZI® (https://imfinzi.com/small-cell-lung-cancer.html)
Title

Immunotherapy for Resectable Stage 2A-3B Non-Small Cell Lung Cancer – IMFINZI®

Meta

Learn about IMFINZI, an immunotherapy option for resectable Stage 2A-3B non-small cell lung cancer (NSCLC) following chemoradiation therapy.

H1 IMFINZI is the first and only immunotherapy approved for both limited-stage and extensive-stage small cell lung cancer (SCLC)
H2 Choose your stage below:
H2 Choose your stage below:
H2 What is IMFINZI?
H2 What is IMFINZI?
H2 What is IMFINZI?
H2 Important Safety Information
H2 Important Safety Information
H2 What is IMFINZI?
H3 What is the most important information I should know about IMFINZI® (durvalumab)?
H3 Call or see your healthcare provider right away if you develop any new or worsening signs or symptoms, including:
H3 What are the possible side effects of IMFINZI?
H3 IMFINZI can cause serious side effects (see above).
H3 What is the most important information I should know about IMFINZI® (durvalumab)?
H3 What is the most important information I should know about IMFINZI® (durvalumab)?
HEADER_HEADING_REPEATED_BODY NSCLC Treatment Options – IMFINZI® (https://imfinzi.com/nsclc.html)
Title

NSCLC Treatment Options – IMFINZI®

Meta

Learn about non-small cell lung cancer (NSCLC) treatment options, including IMFINZI, an FDA-approved immunotherapy that may be part of your treatment plan.

H1 IMFINZI could help you fight non-small cell lung cancer
H2 Select your SCLC stage
H2 If you’ve been diagnosed with NSCLC, it's crucial you know all your options. IMFINZI is an FDA-approved immunotherapy that could be an important part of your personalized treatment plan.
H2 Ask your care team about your options
H2 What are IMFINZI and IMJUDO?
H2 What are IMFINZI and IMJUDO?
H2 Important Safety Information
H2 Important Safety Information
H2 What are IMFINZI and IMJUDO?
H3 Stage 2A-3B cancer that can be removed by surgery
H3 Stage 3 cancer—that can't be treated with surgery—following CRT
H3 Stage 4 cancer that's spread to other parts of the body
H3 What is the most important information I should know about IMFINZI® (durvalumab) and IMJUDO® (tremelimumab-actl)?
H3 Call or see your healthcare provider right away if you develop any new or worsening signs or symptoms, including:
H3 What are the possible side effects of IMFINZI and IMJUDO?
H3 IMFINZI and IMJUDO can cause serious side effects (see above).
H3 What is the most important information I should know about IMFINZI® (durvalumab) and IMJUDO® (tremelimumab-actl)?
H3 What is the most important information I should know about IMFINZI® (durvalumab) and IMJUDO® (tremelimumab-actl)?
H6 Not sure if surgery is an option?
HEADER_HEADING_REPEATED_BODY Treatment for Stomach (Gastric) and GEJ Cancer – IMFINZI® (https://imfinzi.com/gc-gejc.html)
Title

Treatment for Stomach (Gastric) and GEJ Cancer – IMFINZI®

Meta

Learn more about IMFINZI, a treatment used with chemotherapy for patients with stomach (gastric) and gastroesophageal junction cancer.

H1 IMFINZI is leading the way in treatment advancements for stomach (gastric) cancer or gastroesophageal junction cancer (adenocarcinoma) that can be removed with surgery. It is the first and only FDA-approved immunotherapy to be used with chemotherapy* before and after surgery, and then alone, for people with these cancer types.
H2 Choose your stage below:
H2 Choose your stage below:
H2 What is IMFINZI?
H2 What is IMFINZI?
H2 What is IMFINZI?
H2 Important Safety Information
H2 Important Safety Information
H2 What is IMFINZI?
H3 What is the most important information I should know about IMFINZI® (durvalumab)?
H3 Call or see your healthcare provider right away if you develop any new or worsening signs or symptoms, including:
H3 What are the possible side effects of IMFINZI?
H3 IMFINZI can cause serious side effects (see above).
H3 What is the most important information I should know about IMFINZI® (durvalumab)?
H3 What is the most important information I should know about IMFINZI?
📝 The Narrative — clean text per page (homepage promise vs. sub-page reality)
HOMEPAGE (https://imfinzi.com) Immunotherapy for Certain Cancers – IMFINZI® (durvalumab)
Sign up for support

[H1] IMFINZI treats multiple types of cancer

[H2] SELECT YOUR CANCER TYPE

[IMG: Non-Small Cell Lung Cancer (NSCLC)]
Non-Small Cell Lung Cancer (NSCLC)

[IMG: Small Cell Lung Cancer (SCLC)]
Small Cell Lung Cancer (SCLC)

[IMG: Removable Stomach (Gastric) or Gastroesophageal Junction Cancer]
Removable Stomach (Gastric) or Gastroesophageal Junction Cancer

Now Approved

[IMG: Unresectable Hepatocellular Carcinoma (uHCC)]
Unresectable Hepatocellular Carcinoma (uHCC)

[IMG: Bile Duct Cancer and Gallbladder Cancer]
Bile Duct Cancer and Gallbladder Cancer

[IMG: Muscle-Invasive Bladder Cancer (MIBC)]
Bladder Cancer

Now approved for a new type

[IMG: Advanced or Recurrent dMMR Endometrial Cancer]
Advanced or Recurrent dMMR Endometrial Cancer

[IMG: Support through IMFINZI Treatment]

Find support throughout treatment Get more information and resources for starting IMFINZI
Sign up for support

[IMG: close-icon]

[H2] Select your SCLC stage

Limited-Stage Small Cell Lung Cancer (LS-SCLC)
Now Approved

Extensive-Stage Small Cell Lung Cancer (ES-SCLC)
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SUB-PAGE (https://imfinzi.com/small-cell-lung-cancer.html) Immunotherapy for Resectable Stage 2A-3B Non-Small Cell Lung Cancer – IMFINZI®
Sign up for support

[H1] IMFINZI is the first and only immunotherapy approved for both limited-stage and extensive-stage small cell lung cancer (SCLC)

IMFINZI can help treat limited-stage small cell lung cancer that has not progressed following platinum-based chemotherapy and radiation therapy given together (cCRT) and previously untreated extensive-stage small cell lung cancer with chemotherapy.* Speak to your care team about your stage of SCLC so you can find the most helpful information here.
Learn more about the stages of SCLC

[IMG: See the Clinical Trial Results for LS-SCLC]
See the clinical trial results for LS-SCLC
[IMG: link icon]

[IMG: See the Clinical Trial Results for ES-SCLC]
See the clinical trial results for ES-SCLC
[IMG: link icon]

[IMG: See How for SCLC IMFINZI Works with other Treatments]
See how IMFINZI works with other treatments
[IMG: link icon]

Tell me more about...

Go

[IMG: link icon]

*Etoposide and either carboplatin or cisplatin.

[IMG: close-icon]

[H2] Choose your stage below:

Limited-stage Small Cell Lung Cancer

Extensive-stage Small Cell Lung Cancer

[IMG: close-icon]

[H2] Choose your stage below:

Limited-stage Small Cell Lung Cancer

Extensive-stage Small Cell Lung Cancer
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SUB-PAGE (https://imfinzi.com/nsclc.html) NSCLC Treatment Options – IMFINZI®
Sign up for support

[H1] IMFINZI could help you fight non-small cell lung cancer

[H2] If you’ve been diagnosed with NSCLC, it's crucial you know all your options. IMFINZI is an FDA-approved immunotherapy that could be an important part of your personalized treatment plan.
Choose a tab below

I don't know my stage
I know my stage

FPO

Doctors use a process called staging to assess the size of your cancer, where it’s located, and whether it’s spread to other parts of the body. Knowing the stage helps different specialists on your care team work together to find a treatment plan that’s right for you.

[H2] Ask your care team about your options

[IMG: Question Mark Icon]
My doctor told me surgery is an option

My doctor told me surgery is an option
Even when surgery is an option, you may also be treated with immunotherapy and chemotherapy before surgery, then immunotherapy alone after. A medical oncologist can partner with your surgeon to choose a treatment plan. They can also let you know how long you'll be on treatment.
Learn about IMFINZI, chemo & surgery

[IMG: Question Mark Icon]
My doctor told me surgery is not an option

My doctor told me surgery is not an option
If surgery isn’t an option, your care team may use a combination of treatments to fight your cancer, including chemoradiation therapy (CRT) then immunotherapy. In fact, IMFINZI is the #1 prescribed immunotherapy* following chemoradiation therapy for Stage 3 NSCLC that can't be removed by surgery.
Learn about IMFINZI after CRT

[IMG: Question Mark Icon]
What if my cancer has spread?

What if my cancer has spread?
During the staging process, your doctors will check to see whether your cancer has spread from where it started. If it has spread to other parts of the body, your care team may use more than one immunotherapy in combination with chemotherapy.
Learn about IMFINZI & IMJUDO

[H6] Not sure if surgery is an option?
Your doctor may recommend surgery based on the size of your cancer and if it has spread. Ask your care team whether you need any tests to find out if surgery is an option for you.
*Based on US prescriptions from Jan 2019 to Jan 2025.
Already know your stage?

[IMG: NSCLC Stage 2A-3B Lung Icon]

[H3] Stage 2A-3B cancer that can be removed by surgery

Visit site

#1 Prescribed Immunotherapy* FOR:
[IMG: NSCLC Stage 3 Lung Icon]

[H3] Stage 3 cancer—that can't be treated with surgery—following CRT

Visit site

[IMG: NSCLC Stage 4 Lung Icon]

[H3] Stage 4 cancer that's spread to other parts of the body

Visit site

*Based on US prescriptions from Jan 2019 to Jan 2025.
I don’t know my stage

Understanding Stage 4 NSCLC
How do IMFINZI + IMJUDO with chemotherapy work together?

Find support for living with Stage 4 NSCLC

I want to learn more about…
Select a topic
Side effects of IMFINZI + IMJUDO with chemotherapy
Talking to my doctor about IMFINZI + IMJUDO with chemotherapy
Where to get community support
How to prepare for infusions
Getting financial assistance
Supporting my loved one

Explore
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SUB-PAGE (https://imfinzi.com/gc-gejc.html) Treatment for Stomach (Gastric) and GEJ Cancer – IMFINZI®
Request a care package

[H1] IMFINZI is leading the way in treatment advancements for stomach (gastric) cancer or gastroesophageal junction cancer (adenocarcinoma) that can be removed with surgery. It is the first and only FDA-approved immunotherapy to be used with chemotherapy* before and after surgery, and then alone, for people with these cancer types.

See the clinical trial results

[IMG: See What to Expect From Treatment Icon]
See what to expect from treatment
[IMG: link icon]

[IMG: Learn how IMFINZI + chemotherapy* Works Icon]
Learn how IMFINZI + chemotherapy* work together

[IMG: link icon]

[IMG: Patient Support Icon]
Find support
[IMG: link icon]

Tell me more about...

Go

[IMG: link icon]

*Fluorouracil, leucovorin, oxaliplatin, and docetaxel (FLOT).

[IMG: close-icon]

[H2] Choose your stage below:

Limited-stage Small Cell Lung Cancer

Extensive-stage Small Cell Lung Cancer

[IMG: close-icon]

[H2] Choose your stage below:

Limited-stage Small Cell Lung Cancer

Extensive-stage Small Cell Lung Cancer
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