Semantic Coherence: Paradromics – Signal Evidence & AI Readability

[IMG: Hand holding the Paradromics Brain-Computer Interface Cortical Module for scale]
Enabling NeurotechnologyParadromics’ brain-computer interface (BCI) platform records brain activity at the highest possible resolution: the individual neuron. Our AI algorithms decode this massive amount of brain-data, enabling the seamless translation of thought into treatments.
[IMG: Hand holding the Paradromics Brain-Computer Interface Cortical Module for scale]
[H4] The Mission
[H2] Data-driven BCI-based technologies for brain health
Our technology will help millions with unmet medical needs suffering from paralysis and movement disorders to chronic pain, addiction, depression, and other mental health conditions.
[H4] The Platform
[H2] Unmatched performance
By varying the location and quantity of brain interfaces, Paradromics’ high-speed BCI platform is poised to unlock new healthcare applications. Our software and core technology models can be adapted to process the most expansive brain-activity data sets in existence.
[H5] Industry-leading data rate
Single neuron recording and a high bandwidth platform enable complex communication and digital tasks.
[H5] Built to last
Proven materials and fully implantable format are designed for long-term use.
[H5] Scalable‍
Supports 1600+ intracortical channels by linking up to 4 implants, each smaller than a dime.
[H5] Advanced AI
Our machine-learning algorithms translate brain signals into actionable health data.

Current Product
[H1] Connexus® Brain-Computer Interface
[IMG: Female hand holding the Connexus Brain-Computer Interface Cortical Module on the tip of her finger for scale]
[H2] Recording individual brain signals that turn thought into action.
Communication is a fundamental human need. The inability to express yourself with family and friends or request basic needs makes living difficult. For people with motor conditions caused by ALS, spinal cord injury, or stroke, speaking or using the computer may be impossible.Connexus BCI enables motor-impaired people to communicate again and to independently use a computer by translating neural signals into synthesized speech, text, and cursor control.INTRODUCING Connexus BCI
[H4] A category-defining BCI
Paradromics combined advanced neuroscience with medical device expertise to create Connexus BCI, leaping beyond 30 years of brain-computer interface (BCI) research.Built for long-term medical use, Connexus BCI is the first high-data rate BCI designed to deliver high performance for the user.Communication at natural speedsReplication of complex mouse and keyboard hand actions*Connexus BCI is an investigational device and is not available for sale in the United States.
[IMG: A female Paradromics team member looking into a microscope to inspect the Paradromics Brain-Computer Interface]
[IMG: The Paradromics Brain-Computer Interface Cortical Module lays face up to show the tiny electrodes smaller than a human hair]
[H3] ADVANCEDNEUROTECHNOLOGY
[H4] Our cortical module packs sophisticatedneurotechnology into
[IMG: The Paradromics Brain-Computer Interface Cortical Module placed next to a dime is smaller in diameter]
[H4] a tiny package that can only be fabricated in the Paradromics' foundry.
[H2] Cosmetically invisible cortical module has clear advantages
Proven materialsBuilt from metals common in medical implants, including a titanium alloy body and platinum-iridium electrodesDirect access to individual brain signalsWith 421 micro electrodes located next to the neurons, patented on-chip processing records massive amounts of dataLongevityBiocompatible materials and a fully implantable format enable Connexus BCI to last a user’s lifetimeBrain friendlyThe Connexus  BCI electrodes are miniaturized to smaller than 40 microns, each thinner than a hairCONNEXUS BCI
[H1] Cosmetically invisible cortical module has clear advantages
[H2] Proven materials
Built from metals common in medical implants, including a titanium alloy body and platinum-iridium electrodes
[IMG: Video of cortical module]
[H2] Direct access to individual brain signals
With 421 micro electrodes located next to the neurons, patented on-chip processing records massive amounts of data
[IMG: Cortical module]
[H2] Longevity
Biocompatible materials and a fully implantable format enable Connexus to last a user’s lifetime
[IMG: Cortical module image]
[H2] Brain friendly
The Connexus electrodes are miniaturized to smaller than 40 microns, each thinner than a hairHow it works
[H2] The Connexus BCI
01A neurosurgeon places the Connexus BCI system under the skin: cortical module, internal transceiver, and extension lead. The surgery uses well-developed techniques common in other healthcare applications.
[IMG: Detailed render of a person using the Connexus Brain-Computer Interface system implanted under the skin]
How it works
[H2] The Connexus BCI
02The microelectrodes of the cortical module extend just below the brain’s surface to gather rich signals from individual neurons in the motor cortex.
[IMG: Stylized illustration of design details of the Connexus Brain-Computer Interface Cortical Module]
How it works
[H2] The Connexus BCI
03This data is sent along a thin, flexible lead to a transceiver in the chest. This disk-shaped transceiver wirelessly transmits data by a secure optical link to a second transceiver worn by the user. The second transceiver powers the system through inductive charging, similar to wireless charging for smartphones.
[IMG: Render of neural data being processed through the Connexus Brain-Computer Interface Cortical Module to the Internal Transceiver along the lead]
How it works
[H2] The Connexus BCI
04The data is then sent to a small computer loaded with advanced language models and AI. The software analyzes the user’s brain data to figure out what they intend to say or do and translates into words (text on a screen or synthesized speech) or enables control of digital devices.
[IMG: Render of a patient in a wheelchair utilizing the Connexus Brain-Computer Interface System]
[IMG: Engineer running a test between the Connexus Brain-Computer Interface]
CLINICAL STUDY APPROVED
[H2] Recruitment is now open.
For the Connexus BCI Clinical Study, we will look for participants near three clinical sites.University of Michigan – led by Study Investigator Matthew Willsey, M.D., Ph.D.Massachusetts General Hospital – led by Study Investigator Daniel Rubin, M.D., Ph.D.UC Davis – led by Study Principal Investigator David Brandman, M.D., Ph.D.Join our growing community to be notified when recruitment opens in other locations.Join The Community
[IMG: Engineer running a test between the Connexus Brain-Computer Interface]

[H1] Join the Paradromics Community
Please complete the form if you’re interested in future clinical information and to be contacted about the Connexus Brain-Computer Interface.Thank you! Your submission has been received!By clicking “submit” you are agreeing that your information may be used to contact you about  participating in this research study and related opportunities, and that it will be handled in accordance with our Privacy Policy.Oops! Something went wrong while submitting the form.Follow usProductsConnexusTempoCompanyAboutNewsCareersBlogPodcastContactBCI usersClinical TrialBCI CommunityFollow us©2026 Paradromics. All rights reserved.LegalConflicts of Interest Policy©2026 Paradromics. All rights reserved.

Am I a candidate?
[H1] Is your speech very hard to understand, or are you unable to talk because of a nerve or muscle problem?
[H4] You may be able to join the Connect-One Clinical Study.
When paralysis makes it hard to talk, it can feel like your voice is cut off from your thoughts. The Connect-One Clinical Study is testing a brain-computer interface (BCI), called Connexus® BCI, to see if it can help rebuild the link between what you want to say and your ability to speak.As one of the first participants, your feedback can help shape a future where you, and countless others, can communicate and live more independently.Get Involved
[H4] See if you qualify for the Connect-One Study.
Answer a few questions to check if you could be a candidate for the Connect-One Clinical Study.Get started
[IMG: A female Paradromics team member looking into a microscope to inspect the Paradromics Brain-Computer Interface]
Brain signals travel from the Connexus Brain Interface to a chest implant.
[H3] Learn About
[H3] The Study
A receiver worn on the chest sends signals to a computer.
[H1] Connect-One is the first study to test the Connexus BCI in people.
After surgery to place the device, the Connexus BCI reads from the brain area that controls speech movement and is designed to turn brain signals into text, a digital voice, or commands for a phone or computer.Participants will meet with the Connect-One Team several times a week to help adjust the system for their communication needs. Support by a dedicated team will continue throughout the 6 year study.Connexus BCI is aninvestigational device limited by United States law to investigational use.
[H1] Do you qualify to participate?
You may qualify if you:Are an adult between 22 and 75 years old.Are diagnosed with a progressive disease (like Amyotrophic Lateral Sclerosis (ALS)) or an injury that affects muscles or nerves (like a brainstem stroke).Have trouble speaking, such as slurred speech (dysarthria) or loss of control over speech muscles (anarthria).Can communicate well enough to agree to join the study and share experiences.Can read and understand English.Have experience using assistive communication devices, like eye-tracking systems.Live within 4 hours of Sacramento, CA, Ann Arbor, MI, or Boston, MA.You will not qualify if you:Have another implanted device, like a pacemaker, deep brain stimulator, or implantable pulse generator.Need regular MRI scans.Require certain treatments, such as Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), or diathermy.
[H1] TO QUALIFY, PARTICIPANTS NEED TO LIVE IN THE UNITED STATES IN ONE OF THESE AREAS:
[H1] Greater Sacramento, CA
[H1] Greater Ann Arbor, MI
[H1] Greater Boston, MA

*The Connect-One Clinical Study is available in the United States only.
[H1] Ready to take the next steps?
[H3] Clinical Trial
Answer a few questions to check if you could be a candidate for the Connect-One Clinical Study.Get started
[H3] BCI Community
Submit your email to stay up to date on study progress and ways to get involved.Join the community