Information Density: Pfizer Inc. – Signal Evidence & AI Readability

[IMG: Woman with COVID-19 holding her COVID test]

[IMG: Woman with COVID-19 holding her COVID test]

[IMG: Woman with COVID-19 holding her COVID test]

Individuals portrayed on this site are actors.

[H1] If it’s COVID,

[H2] Paxlovid®.

PAXLOVID is a prescription treatment for mild-to-moderate COVID-19 in adults who are at high risk for progression to severe COVID, including hospitalization or death.
Learn how to get PAXLOVID

PAXLOVID is also authorized for certain people under an Emergency Use Authorization. Learn more.

PAXLOVID is also authorized for certain people under an Emergency Use Authorization. Learn more.

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[H1] It may be mild now, but don't wait—treatment must be taken within 5 days of symptoms
COVID still makes some people very sick, especially people who are at high risk for progression to severe COVID. If you wait too long to treat COVID, it may be too late to stop severe illness.
PAXLOVID is not approved for use as pre-exposure or post-exposure treatment for prevention of COVID. There are certain medications that should not be taken with PAXLOVID. Talk to your healthcare professional to see if PAXLOVID is right for you.

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75% of American adults have a high risk factor for severe COVID. If you're one of them and tested positive for COVID, PAXLOVID could be an option for you.
Is it right for me?

PAXLOVID is indicated for adults with a high-risk factor for severe COVID. It’s a prescription medication that can help prevent mild-to-moderate COVID from becoming severe.
Why treatment matters

If you have COVID and are 50 years of age or older, or have certain underlying conditions, you should talk to your doctor about treatment options.
Get PAXLOVID

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[IMG: Man in robe sick with COVID holding a tissue]

[IMG: Man in robe sick with COVID holding a tissue]

[IMG: Man in robe sick with COVID holding a tissue]

[H2] 3 out of 4 adults have a higher chance of getting very sick with severe COVID
Some of the most common risk factors for progression to severe COVID include:
Age of 50+ years
Certain health conditions and diseases—such as heart disease and diabetes
Being overweight or obese
Mental health conditions
Lifestyle factors, such as smoking
Physical, mental, and developmental disabilities
Your risk also increases if you are unvaccinated or not up to date with vaccinations against COVID, or you experience healthcare access inequities due to race, ethnicity, disability, or where you live or work.
Your risk may also be increased by other factors not listed on this site, so be sure to discuss all of your health conditions and lifestyle factors with your healthcare professional.

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Eligible commercially insured patients may access PAXLOVID for as little as $0* and eligible Medicare, Medicaid, and uninsured patients may access PAXLOVID for free†
Discover PAXCESS
*Eligible commercially insured patients can save up to a maximum of $1,000 annually. Terms and conditions apply.
†Eligible government insured and uninsured patients can access PAXLOVID for free through December 31, 2026. The USG PAP operated by Pfizer is an independent program with separate eligibility requirements offered by the United States Department of Health and Human Services and is not owned by Pfizer. Terms and conditions apply.

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[H2] Navigate your next treatment journey confidently
Sign up to receive PAXLOVID information to help you make informed decisions in case you get sick.
Sign up now

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[H3] For more information
Contact by using one of the following methods:
For medical information, visit www.pfizermedicalinformation.com or call 1-800-438-1985
For general product inquiries, call 1-877-219-7225

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Quick links
Safety, Side Effects & Drug Interactions
Why Take PAXLOVID
Who Can Take PAXLOVID
How to Get PAXLOVID

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[IMG: Man with COVID on a telehealth call with a health care provider]

[IMG: Man with COVID on a telehealth call with a health care provider]

[H1] How to get

[H2] Paxlovid®.

PAXLOVID is only available by prescription and must be started within the first 5 days of COVID‑19 symptoms. Here are some key steps for working with your healthcare professional to determine if PAXLOVID may be right for you.
Individuals portrayed on this site are actors.

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[H2] Getting started on PAXLOVID
Think PAXLOVID is right for you? Follow these steps:

1
Know if you have a condition or a risk factor that increases your chances of getting very sick with COVID

Your risk of getting severely ill with COVID is increased by many health conditions, lifestyle factors, disabilities, and more. Some of the more common high-risk factors include:
Age of 50+ years
Certain health conditions and diseases, such as heart disease and diabetes
Being overweight or obese
Mental health conditions
Lifestyle factors, such as smoking
Physical, mental, and developmental disabilities
See more risk factors

2
As soon as you notice symptoms of COVID, get tested and reach out to your healthcare professional

Symptoms may include, but are not limited to:
Fever or chills
Cough
Shortness of breath or difficulty breathing
Fatigue
Muscle or body aches
Headache
New loss of taste or smell
Sore throat
Congestion or runny nose
Nausea or vomiting
Diarrhea

3
If you test positive, work with your healthcare professional to get a PAXLOVID prescription, if appropriate
Once you fill your prescription, start taking PAXLOVID that morning or evening, or at the time your healthcare professional recommends. Remember, PAXLOVID must be started within the first 5 days of COVID symptoms.

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[H2] Your Doctor Discussion Guide
Here’s a discussion guide that goes over what you should review at your next appointment. Things like medicines or supplements you’re currently taking matter before starting treatment.
Download Discussion Guide

[IMG: Man with COVID on the phone outside contacting a healthcare professional]

[IMG: Man with COVID on the phone outside contacting a healthcare professional]

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[H2] Prescribed PAXLOVID?

[H2] See if you can save
Explore cost-saving options

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Quick links
FAQs
Why Take PAXLOVID
Who Can Take PAXLOVID

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[IMG: Man with COVID holding an iPad]

[IMG: Man with COVID holding an iPad]

[H2] Safety, Side Effects, & Drug Interactions
Before you take PAXLOVID, you should know the benefits as well as the risks, including medications that cannot be taken with PAXLOVID.
Please be sure to review this information with your healthcare professional.
Individuals portrayed on this site are actors.

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[H1] Talk to your healthcare provider about these important considerations before taking PAXLOVID
There are many important topics to discuss with your doctor about taking PAXLOVID, including possible side effects, drug interactions, and safety concerns in the drop-down lists below.
There could be additional considerations not found in these lists as well, so be sure to check with your healthcare provider.

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[H2] Key Safety Topics to Discuss

https://main--paxlovidcompaxlovid--pfizer.hlx.page/global/fragments/key-safety-topics-side-effects

[H2] Medications That Cannot Be Taken With PAXLOVID

Taking certain medicines with PAXLOVID can cause severe or life-threatening side effects or death
It is very important to tell your healthcare professional about all of the medicines you are taking because additional laboratory tests or changes in the dose of your other medicines may be necessary during treatment with PAXLOVID
Your healthcare professional may also tell you about specific symptoms to watch out for that may indicate that you need to stop or decrease the dose of some of your other medicines
The table below is not a complete list of all medicines that cannot be taken with PAXLOVID. PAXLOVID may increase or decrease the levels of other medicines

https://main--paxlovidcompaxlovid--pfizer.hlx.page/global/fragments/medications

[H2] Possible Side Effects
PAXLOVID may cause side effects, some of which may be serious, such as allergic reactions or liver problems. The list below doesn't include all of the possible side effects of PAXLOVID. For more information, ask your healthcare professional or pharmacist.
[H3] Some side effects of PAXLOVID are:

[H2] Allergic Reactions
Stop taking PAXLOVID and call your healthcare professional right away if you get any of the following symptoms of an allergic reaction:
Hives, skin rash, blisters, or peeling skin
Painful sores or ulcers in the mouth, nose, throat, or genital area
Trouble swallowing or breathing
Swelling of the mouth, lips, tongue, or face
Throat tightness
Hoarseness of voice

[H2] Liver Problems
Tell your healthcare professional right away if you have any of these signs and symptoms of liver problems:
Loss of appetite
Yellowing of your skin and the whites of your eyes (jaundice)
Dark-colored urine
Pale-colored stools
Itchy skin
Stomach-area (abdominal) pain

[H2] Most Common Side Effects

Altered sense of taste (such as metallic, bitter taste)
Diarrhea

[H2] Other Possible Side Effects

Headache
Vomiting
Stomach-area (abdominal) pain
Nausea
High blood pressure
Feeling generally unwell

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Contact your healthcare professional if you have any side effects that bother you or do not go away.
Patients should always ask their doctors for medical advice about adverse events. You are encouraged to report adverse events related to Pfizer products by calling 1-800-438-1985 (U.S. only). If you prefer, you may contact the U.S. Food and Drug Administration (FDA) directly. Visit www.fda.gov/medwatch* or call 1-800-FDA-1088.
Please see full Prescribing Information, including BOXED WARNING and Important Facts.
By clicking this link, you will be redirected to a website that is neither owned nor controlled by Pfizer. Pfizer is not responsible for the content or services of this site.

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[H2] Your Doctor Discussion Guide
Here’s a discussion guide that goes over what you should review at your next appointment. Things like medicines or supplements you’re currently taking matter before starting treatment.
Download Discussion Guide

[IMG: Man with COVID on the phone outside contacting a healthcare professional]

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[H2] Getting started on PAXLOVID
See if you could be eligible to start prescription medication today.
Find out more

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Quick links
Safety, Side Effects, & Drug Interactions
Why Take PAXLOVID
Who Can Take PAXLOVID
How to Get PAXLOVID

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[IMG: Woman outside holding a mug]

[IMG: Woman outside holding a mug]

[H1] Who can take

[H2] Paxlovid®.

If you have mild-to-moderate COVID-19 and have at least one high risk factor increasing your chances of getting very sick from COVID, PAXLOVID could be an option for you.
Individuals portrayed on this site are actors.

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[H3] 3 out of 4 adults have a risk factor for progression to severe COVID
You might not know this, but a majority of American adults have at least one risk factor putting them at greater risk of progression to severe COVID. If you have mild-to-moderate COVID, have had symptoms for 5 days or fewer, and have one of the risk factors listed below (including being age 50 or over), PAXLOVID could be an option for you.
According to the US Centers for Disease Control and Prevention (CDC), your risk of progressing to severe COVID may also be increased if you:
Are unvaccinated or not up to date with vaccinations against COVID
Experience healthcare access inequities due to race, ethnicity, disability, or where you live or work

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[H2] Talk to your doctor about treatment if you tested positive and have any of the conditions below. Your chances of COVID getting worse are higher.

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[H2] Detailed List of High Risk Factors

Age

The CDC recommends treatment for anyone 50 and older
People who are 65 years of age or older are at the highest risk

Physical Diseases and Conditions
Blood disorders
Sickle cell disease or thalassemia
Cancer
Cerebrovascular disease
Stroke
Chronic kidney problems
People with moderate-to-severe renal impairment will need different doses or dosing schedules of PAXLOVID
Chronic liver problems
Cirrhosis (or scarring of the liver)
Non-alcoholic fatty liver disease
Alcohol-related liver disease
Autoimmune hepatitis
PAXLOVID is not recommended for people with severe liver disease
Chronic lung diseases
Moderate-to-severe asthma
Bronchiectasis (thickening of the lungs’ airways)
A chronic lung disease affecting newborns called bronchopulmonary dysplasia
Chronic obstructive pulmonary disease (COPD), including emphysema and chronic bronchitis
Damaged or scarred lung tissue known as interstitial lung disease (including idiopathic pulmonary fibrosis)
Pulmonary embolism (blood clot in the lungs)
Pulmonary hypertension (high blood pressure in the lungs)
Cystic fibrosis
Diabetes type 1 and type 2
Heart conditions
Heart failure
Coronary artery disease (damage or disease in the heart's major blood vessels)
Cardiomyopathies (heart muscle diseases)
Possibly high blood pressure (hypertension)
Infections and other contagious illnesses
Human immunodeficiency virus (HIV)
Tuberculosis
Neurological conditions
Dementia
Weakened immune system, which may be caused by:
Solid organ or blood stem cell transplant
Corticosteroids, chemotherapy, or other medicines that reduce immune function
Primary immunodeficiency

Weight
An overweight or obese body mass index (BMI) of 25 or higher is a risk factor for adults.
Don’t know your BMI? Calculate it here*
*By clicking this link, you will be redirected to a website that is neither owned nor controlled by Pfizer. Pfizer is not responsible for the content or services of this site.

Pregnancy
Your risk is increased if you are pregnant or were pregnant within the last 6 weeks. It’s not known if PAXLOVID is safe to use during pregnancy, so be sure to tell your healthcare professional if you are pregnant or have been pregnant within the last few months.

Mental Health Conditions
Mental health conditions increase your risk, including:
Mood disorders, such as depression
Schizophrenia spectrum disorders

Lifestyle Factors

Doing little or no physical activity
Current or former smoker
Substance use disorders (such as alcohol, opioid, or cocaine use disorders)

Disabilities
Some mental, physical, and developmental disabilities increase risk, including those that:
Limit mobility
Reduce a person’s ability to follow preventive measures, like hand washing
Require close contact with those who may be infected, such as a caregiver or family member
Reduce a person’s ability to communicate their symptoms
These disabilities put you at risk:
Attention-Deficit/Hyperactivity Disorder (ADHD)
Autism
Cerebral Palsy
Charcot Foot
Chromosomal Disorders
Chromosome 17 and 19 Deletion
Chromosome 18q Deletion
Cognitive Impairment
Congenital Hydrocephalus
Congenital Malformations
Deafness/Hearing Loss
Disability Indicated by Barthel Index
Down Syndrome
Fahr’s Syndrome
Fragile X Syndrome
Gaucher Disease
Hand and Foot Disorders
Learning disabilities
Leber’s Hereditary Optic Neuropathy (LHON) or Autosomal Dominant Optic Atrophy (ADOA)
Leigh Syndrome
Limitations with self-care or activities of daily living
Maternal Inherited Diabetes and Deafness (MIDD)
Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes (MELAS) and Risk Markers
Mobility Disability
Movement Disorders
Multiple Disability (referred to in research papers as “bedridden disability”)
Multisystem Disease
Myoclonic Epilepsy with Ragged Red Fibers (MERRF)
Myotonic Dystrophy
Neurodevelopmental Disorders
Neuromuscular Disorders
Neuromyelitis Optica Spectrum Disorder (NMOSD)
Neuropathy, Ataxia, and Retinitis Pigmentosa (NARP)
Perinatal Spastic Hemiparesis
Primary Mitochondrial Myopathy (PMM)
Progressive Supranuclear Palsy
Senior-Løken Syndrome
Severe and complex disability (referred to in research papers as “polyhandicap disability”)
Spina Bifida and Other Nervous System Anomalies
Spinal Cord Injury
Tourette Syndrome
Traumatic Brain Injury
Visual Impairment/Blindness
Wheelchair Use

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[H3] Additional information to share with your healthcare professional when discussing PAXLOVID

Be sure to let your healthcare professional know if you have any allergies
Do not take PAXLOVID if you’re allergic to nirmatrelvir, ritonavir, or any of the ingredients in PAXLOVID.

Come with a list of all the medicines you take
Including all of your prescription and over-the-counter medicines, vitamins, and herbal supplements. PAXLOVID can interact with other medicines causing severe or life-threatening side effects or death. Be sure to tell your healthcare professional about all the medicines you take when discussing PAXLOVID.

PAXLOVID may affect how oral contraceptives work
If you are able to become pregnant, you should discuss birth control with your healthcare professional. You may need to use a different or additional form of contraception.

Tell your healthcare professional if you have liver or kidney problems or have HIV infection
If you have any recent blood test results, bring them for your healthcare professional to review. PAXLOVID isn’t for people with severe liver disease. PAXLOVID may lead to some HIV medicines not working as well in the future.

Tell your healthcare professional if you are pregnant, plan to become pregnant, are breastfeeding, or plan to breastfeed
PAXLOVID can pass into your breast milk. Talk to your healthcare provider about the best way to feed your baby during treatment with PAXLOVID.

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[H2] Don’t wait if you have any of the conditions listed above.
If you wait too long to treat COVID, it may be too late to help stop severe illness. PAXLOVID must be started within 5 days of symptom onset.
Learn how to get

[IMG: Man with COVID coughing with concerned wife in background]

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Quick links
Why Take PAXLOVID
How to Get PAXLOVID

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