Identity & Authority: XTANDI (Astellas Pharma Inc.) – Signal Evidence & AI Readability

XTANDI (Astellas Pharma Inc.)

(https://xtandi.com) 📸 Data Snapshot: June 20, 2026
Identity & Authority — The Lens

Inspect the JSON-LD. Is there an Organization or Person schema, and does it carry sameAs links to real external profiles (LinkedIn, socials)? Missing schema or no identity declaration signals an anonymous entity.

Identity & Authority Expert verifiability & Schema depth.
15 Impact Weight: 15 / 100
100% Reputation

No authority gaps were detected. The manufacturer (Astellas) is clearly identified in the footer and structured data, and the drug is identified by its non-proprietary name (enzalutamide). The site does not rely on unverifiable ‘expert’ endorsements but instead points users toward their own healthcare professionals via the Doctor Discussion Guide.

There is no disconnect between marketing claims and clinical performance. Bold assertions like ‘61% less risk of cancer progression’ are immediately followed by raw trial numbers (89 out of 576 patients) and a clear definition of how progression was measured (scans or death). This level of transparency is characteristic of compliant pharmaceutical communications.

Identity & Authority is read from the structured data first: whether the site declares who it is in machine-readable schema, with verifiable identity links. Below is the schema captured per page, then the external proof links that support (or fail to support) that identity.

🔗 Identity & Technical Layer — schema JSON-LD: identity chains, entity gaps
Homepage schema
{
    "@context": "http://schema.org",
    "@type": "MedicalWebPage",
    "audience": "https://schema.org/Patient",
    "specialty": "https://schema.org/Oncologic",
    "url": "https://www.xtandi.com/",
    "name": "XTANDI® (enzalutamide) | Advanced Prostate Cancer Treatment",
    "headline": "*",
    "description": "XTANDI® is an androgen receptor inhibitor (ARI) used for the treatment of four types of advanced prostate cancer, including mCRPC, nmCRPC, mCSPC, and nmCSPC with rapidly rising PSA. See Important Safety Information, Risks, and Benefits.",
    "potentialAction": [
        {
            "@type": "Action",
            "name": "Learn more",
            "description": "Savings & Support: Find out more information about financial support options that may help eligible patients.",
            "url": "https://www.xtandi.com/financial-support"
        },
        {
            "@type": "Action",
            "name": "Watch their stories",
            "description": "Gain perspective into the lives of men living with advanced prostate cancer and taking XTANDI.",
            "url": "https://www.xtandi.com/patient-videos"
        },
        {
            "@type": "Action",
            "name": "Watch story",
            "description": "The Power of Support",
            "url": "https://www.xtandi.com/patient-videos/power-of-support"
        },
        {
            "@type": "Action",
            "name": "Watch story",
            "description": "Self-Advocating",
            "url": "https://www.xtandi.com/patient-videos/self-advocating"
        },
        {
            "@type": "Action",
            "name": "Watch story",
            "description": "Journey to Access",
            "url": "https://www.xtandi.com/patient-videos/journey-to-access"
        },
        {
            "@type": "Action",
            "name": "Watch story",
            "description": "Advice",
            "url": "https://www.xtandi.com/patient-videos/advice"
        },
        {
            "@type": "Action",
            "name": "Watch story",
            "description": "Treatment",
            "url": "https://www.xtandi.com/patient-videos/treatment"
        },
        {
            "@type": "Action",
            "name": "Learn more",
            "description": "Select Safety Information",
            "url": "https://www.xtandi.com/side-effects"
        },
        {
            "@type": "Action",
            "name": "Sign up",
            "description": "Sign up for support emails and resources",
            "url": "https://www.xtandi.com/support-sign-up"
        }
    ],
    "about": [
        {
            "@type": "Drug",
            "name": "XTANDI",
            "nonProprietaryName": "enzalutamide",
            "image": {
                "@type": "ImageObject",
                "name": "XTANDI® (enzalutamide) 40 mg tablets | 80 mg tablets",
                "description": "XTANDI Logo",
                "contentUrl": "https://www.xtandi.com/images/xtandi-logo.svg"
            },
            "description": "What is XTANDI? XTANDI is a prescription medicine used to treat men with prostate cancer that: no longer responds to a hormone therapy or surgical treatment to lower testosterone OR has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone OR has not spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone, and who are at high risk of cancer spreading to other parts of the body. It is not known if XTANDI is safe and effective in females or children.",
            "prescribingInfo": "https://www.astellas.us/docs/us/12A005-ENZ-WPI.pdf",
            "warning": "What should I tell my doctor before taking XTANDI? Tell your doctor about all your medical conditions, including if you:  Have a history of seizures, brain injury, stroke, or brain tumors. Have a history of heart disease, have high blood pressure, or have abnormal amounts of fat or cholesterol in your blood (dyslipidemia). Are pregnant or plan to become pregnant. XTANDI can cause harm to your unborn baby and loss of pregnancy (miscarriage). Have a partner who is pregnant or may become pregnant. Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with XTANDI and for 3 months after the last dose. Males must use a condom during sex with a pregnant female. Are breastfeeding or plan to breastfeed. It is not known if XTANDI passes into your breast milk. Take other medicines. XTANDI may affect the way other medicines work, and other medicines may affect how XTANDI works. These include prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not start or stop any medicine without talking to your doctor. How should I take XTANDI? Take XTANDI exactly as your doctor tells you. Take your prescribed dose once a day, at the same time each day. XTANDI can be taken with or without food. Swallow XTANDI capsules or tablets whole. Do not chew, dissolve, or open the capsules. Do not cut, crush or chew the tablets. Your doctor may change your dose if needed. Do not change or stop taking your prescribed dose of XTANDI without talking with your doctor first. If you are receiving gonadotropin-releasing hormone (GnRH) therapy, you should continue with this treatment while taking XTANDI unless you have had surgery to lower the amount of testosterone in your body (surgical castration). If you miss a dose of XTANDI: Take your prescribed dose as soon as you remember that day. If you miss your daily dose, take your prescribed dose at your regular time the next day. Do not take more than your prescribed dose of XTANDI each day. If you take too much XTANDI: Call your doctor or go to the nearest emergency room right away. You may have an increased risk of seizure if you take too much XTANDI. What are the possible side effects of XTANDI? XTANDI may cause serious side effects including:  Seizure. If you take XTANDI, you may be at risk of having a seizure. Avoid activities where a sudden loss of consciousness could seriously harm you or someone else. Tell your doctor right away if you lose consciousness or have a seizure. Posterior Reversible Encephalopathy Syndrome (PRES). If you take XTANDI you may be at risk of developing a condition involving the brain called PRES. Tell your doctor right away if you have a seizure or quickly worsening symptoms such as headache, decreased alertness, confusion, reduced eyesight, blurred vision or other visual problems. Your doctor will do a test to check for PRES. Allergic Reactions. Allergic reactions have happened in people who take XTANDI. Stop taking XTANDI and get medical help right away if you develop swelling of the face, tongue, lip or throat. Heart Disease. Blockage of the arteries in the heart (ischemic heart disease) that can lead to death has happened in some people during treatment with XTANDI. Your doctor will monitor you for signs and symptoms of heart problems during your treatment. Call your doctor or go to the emergency room right away if you get chest pain or discomfort at rest or with activity or shortness of breath during your treatment with XTANDI. Falls and Bone Fractures. XTANDI treatment may increase your risk for falls and bone fractures. Falls were not caused by loss of consciousness or seizures. Your doctor will monitor your risks for falls and bone fractures during treatment with XTANDI. Your doctor will stop treatment with XTANDI if you have serious side effects.  The most common side effects of XTANDI include: Muscle and joint pain Feeling more tired than usual Hot flashes Constipation Decreased appetite Diarrhea High blood pressure Bleeding problems Falls Bone fractures Headache XTANDI may cause fertility problems in males, which may affect the ability to father children. Talk to your doctor if you have concerns about fertility.  These are not all the possible side effects of XTANDI. For more information, talk to your doctor or pharmacist.  Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.  For further information, please talk to your doctor and click here for Patient Information and Full Prescribing Information for XTANDI.",
            "prescriptionStatus": "https://health-lifesci.schema.org/PrescriptionOnly",
            "dosageForm": "tablets",
            "administrationRoute": "oral",
            "doseSchedule": {
                "@type": "DoseSchedule",
                "frequency": "XTANDI is taken by mouth and is available in 2 dosage strengths: 40 mg and 80 mg. Take XTANDI once a day, at the same time every day, with or without food."
            },
            "offers": {
                "@type": "Offer",
                "price": "0",
                "priceCurrency": "USD",
                "url": "https://www.xtandi.com/"
            },
            "manufacturer": {
                "@type": "Organization",
                "name": "Astellas",
                "logo": "https://www.xtandi.com/img/logo-astellas.png"
            }
        }
    ]
}
/clinical-trials/
{
    "0": {
        "@context": "http://schema.org",
        "@type": "MedicalWebPage",
        "audience": "https://schema.org/Patient",
        "specialty": "https://schema.org/Oncologic",
        "url": "https://www.xtandi.com/clinical-trials",
        "name": "Clinical Trial Results | XTANDI® (enzalutamide)",
        "headline": "XTANDI is FDA-approved to treat 4 types of advanced prostate cancer",
        "description": "Explore the clinical trial results of XTANDI®, an FDA-approved treatment for 4 types of advanced prostate cancer. See Important Safety Information, Risks, and Benefits.",
        "mainEntity": [
            {
                "name": "In multiple clinical studies, XTANDI® (enzalutamide) was proven to delay cancer progression and helped men live longer"
            },
            {
                "@type": "ListItem",
                "position": "1",
                "name": "Metastatic castration-sensitive prostate cancer (mCSPC)",
                "description": "Prostate cancer that has spread to other parts of the body and responds to hormone therapy or surgical treatment to lower testosterone.",
                "url": "https://www.adcetris.com/static/adcetris-treatment-decision-guide-d132e78b194b56bc174108130719df76.pdf"
            },
            {
                "@type": "ListItem",
                "position": "2",
                "name": "Metastatic castration-resistant prostate cancer (mCRPC)",
                "description": "Prostate cancer that has spread to other parts of the body and no longer responds to a hormone therapy or surgical treatment to lower testosterone."
            },
            {
                "@type": "ListItem",
                "position": "3",
                "name": "Non-metastatic castration-resistant prostate cancer (nmCRPC)",
                "description": "Prostate cancer that has not spread to other parts of the body and no longer responds to a hormone therapy or surgical treatment to lower testosterone."
            }
        ],
        "potentialAction": [
            {
                "@type": "Action",
                "name": "Overall Survival",
                "description": "XTANDI helped men live longer",
                "url": "https://www.xtandi.com/clinical-glossary?keyword=overall-survival"
            },
            {
                "@type": "Action",
                "name": "Learn more",
                "description": "XTANDI may cause serious side effects including falls and fractures.",
                "url": "https://www.xtandi.com/side-effects"
            },
            {
                "@type": "Action",
                "name": "Watch their stories",
                "description": "Hear firsthand from men who are taking XTANDI",
                "url": "https://www.xtandi.com/patient-stories"
            },
            {
                "@type": "Action",
                "name": "Review guide",
                "description": "Need to prepare for your next doctor’s visit?",
                "url": "https://www.xtandi.com/doctor-discussion-guide"
            },
            {
                "@type": "Action",
                "name": "Learn more",
                "description": "Explore our glossary of prostate cancer terms",
                "url": "https://www.xtandi.com/clinical-glossary"
            }
        ],
        "about": [
            {
                "@type": "Drug",
                "name": "XTANDI",
                "nonProprietaryName": "enzalutamide",
                "image": {
                    "@type": "ImageObject",
                    "name": "XTANDI® (enzalutamide) 40 mg tablets | 80 mg tablets",
                    "description": "XTANDI Logo",
                    "contentUrl": "https://www.xtandi.com/images/xtandi-logo.svg"
                },
                "description": "What is XTANDI? XTANDI is a prescription medicine used to treat men with prostate cancer that: no longer responds to a hormone therapy or surgical treatment to lower testosterone OR has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone OR has not spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone, and who are at high risk of cancer spreading to other parts of the body. It is",
                "prescribingInfo": "https://www.astellas.us/docs/us/12A005-ENZ-WPI.pdf",
                "warning": "What should I tell my doctor before taking XTANDI? Tell your doctor about all your medical conditions, including if you:  Have a history of seizures, brain injury, stroke, or brain tumors. Have a history of heart disease, have high blood pressure, or have abnormal amounts of fat or cholesterol in your blood (dyslipidemia). Are pregnant or plan to become pregnant. XTANDI can cause harm to your unborn baby and loss of pregnancy (miscarriage). Have a partner who is pregnant or may become pregnant. ",
                "study": [
                    {
                        "@type": "[DEPTH_TRUNCATED]",
                        "name": "[DEPTH_TRUNCATED]",
                        "trialDesign": "[DEPTH_TRUNCATED]",
                        "description": "[DEPTH_TRUNCATED]",
                        "image": "[DEPTH_TRUNCATED]"
                    },
                    {
                        "@type": "[DEPTH_TRUNCATED]",
                        "name": "[DEPTH_TRUNCATED]",
                        "trialDesign": "[DEPTH_TRUNCATED]",
                        "description": "[DEPTH_TRUNCATED]",
                        "image": "[DEPTH_TRUNCATED]"
                    },
                    {
                        "@type": "[DEPTH_TRUNCATED]",
                        "name": "[DEPTH_TRUNCATED]",
                        "trialDesign": "[DEPTH_TRUNCATED]",
                        "description": "[DEPTH_TRUNCATED]",
                        "image": "[DEPTH_TRUNCATED]"
                    },
                    {
                        "@type": "[DEPTH_TRUNCATED]",
                        "name": "[DEPTH_TRUNCATED]",
                        "trialDesign": "[DEPTH_TRUNCATED]",
                        "description": "[DEPTH_TRUNCATED]",
                        "image": "[DEPTH_TRUNCATED]"
                    }
                ],
                "prescriptionStatus": "https://health-lifesci.schema.org/PrescriptionOnly",
                "dosageForm": "tablets",
                "administrationRoute": "oral",
                "doseSchedule": {
                    "@type": "DoseSchedule",
                    "frequency": "XTANDI is taken by mouth and is available in 2 dosage strengths: 40 mg and 80 mg. Take XTANDI once a day, at the same time every day, with or without food."
                },
                "offers": {
                    "@type": "Offer",
                    "price": "0",
                    "priceCurrency": "USD",
                    "url": "https://www.xtandi.com/"
                },
                "manufacturer": {
                    "@type": "Organization",
                    "name": "Astellas",
                    "logo": "https://www.xtandi.com/img/logo-astellas.png"
                }
            }
        ]
    },
    "_truncated": true,
    "_original_size": 15978
}
/talking-to-your-doctor/
{
    "@context": "http://schema.org",
    "@type": "MedicalWebPage",
    "audience": "https://schema.org/Patient",
    "specialty": "https://schema.org/Oncologic",
    "url": "https://www.xtandi.com/talking-to-your-doctor",
    "name": "XTANDI® (enzalutamide) Doctor Discussion Guide",
    "headline": "Questions for your next appointment",
    "description": "See the XTANDI® Doctor Discussion Guide, which includes questions for your doctor about advanced prostate cancer and XTANDI®. See Safety Info, Risks, & Benefits.",
    "potentialAction": [
        {
            "@type": "downloadAction",
            "name": "Download this guide",
            "url": "https://www.xtandi.com/pdf/xtandi-doctor-discussion-guide.pdf"
        },
        {
            "@type": "Action",
            "name": "Explore resources",
            "url": "https://www.xtandi.com/patient-resources"
        },
        {
            "@type": "Action",
            "name": "Watch their stories",
            "url": "https://www.xtandi.com/patient-videos"
        },
        {
            "@type": "Action",
            "name": "Sign up",
            "url": "https://www.xtandi.com/support-sign-up"
        }
    ],
    "about": [
        {
            "@type": "Drug",
            "name": "XTANDI",
            "nonProprietaryName": "enzalutamide",
            "image": {
                "@type": "ImageObject",
                "name": "XTANDI® (enzalutamide) 40 mg tablets | 80 mg tablets",
                "description": "XTANDI Logo",
                "contentUrl": "https://www.xtandi.com/images/xtandi-logo.svg"
            },
            "description": "What is XTANDI? XTANDI is a prescription medicine used to treat men with prostate cancer that: no longer responds to a hormone therapy or surgical treatment to lower testosterone OR has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone OR has not spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone, and who are at high risk of cancer spreading to other parts of the body. It is not known if XTANDI is safe and effective in females or children.",
            "prescribingInfo": "https://www.astellas.us/docs/us/12A005-ENZ-WPI.pdf",
            "warning": "What should I tell my doctor before taking XTANDI? Tell your doctor about all your medical conditions, including if you:  Have a history of seizures, brain injury, stroke, or brain tumors. Have a history of heart disease, have high blood pressure, or have abnormal amounts of fat or cholesterol in your blood (dyslipidemia). Are pregnant or plan to become pregnant. XTANDI can cause harm to your unborn baby and loss of pregnancy (miscarriage). Have a partner who is pregnant or may become pregnant. Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with XTANDI and for 3 months after the last dose. Males must use a condom during sex with a pregnant female. Are breastfeeding or plan to breastfeed. It is not known if XTANDI passes into your breast milk. Take other medicines. XTANDI may affect the way other medicines work, and other medicines may affect how XTANDI works. These include prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not start or stop any medicine without talking to your doctor. How should I take XTANDI? Take XTANDI exactly as your doctor tells you. Take your prescribed dose once a day, at the same time each day. XTANDI can be taken with or without food. Swallow XTANDI capsules or tablets whole. Do not chew, dissolve, or open the capsules. Do not cut, crush or chew the tablets. Your doctor may change your dose if needed. Do not change or stop taking your prescribed dose of XTANDI without talking with your doctor first. If you are receiving gonadotropin-releasing hormone (GnRH) therapy, you should continue with this treatment while taking XTANDI unless you have had surgery to lower the amount of testosterone in your body (surgical castration). If you miss a dose of XTANDI: Take your prescribed dose as soon as you remember that day. If you miss your daily dose, take your prescribed dose at your regular time the next day. Do not take more than your prescribed dose of XTANDI each day. If you take too much XTANDI: Call your doctor or go to the nearest emergency room right away. You may have an increased risk of seizure if you take too much XTANDI. What are the possible side effects of XTANDI? XTANDI may cause serious side effects including:  Seizure. If you take XTANDI, you may be at risk of having a seizure. Avoid activities where a sudden loss of consciousness could seriously harm you or someone else. Tell your doctor right away if you lose consciousness or have a seizure. Posterior Reversible Encephalopathy Syndrome (PRES). If you take XTANDI you may be at risk of developing a condition involving the brain called PRES. Tell your doctor right away if you have a seizure or quickly worsening symptoms such as headache, decreased alertness, confusion, reduced eyesight, blurred vision or other visual problems. Your doctor will do a test to check for PRES. Allergic Reactions. Allergic reactions have happened in people who take XTANDI. Stop taking XTANDI and get medical help right away if you develop swelling of the face, tongue, lip or throat. Heart Disease. Blockage of the arteries in the heart (ischemic heart disease) that can lead to death has happened in some people during treatment with XTANDI. Your doctor will monitor you for signs and symptoms of heart problems during your treatment. Call your doctor or go to the emergency room right away if you get chest pain or discomfort at rest or with activity or shortness of breath during your treatment with XTANDI. Falls and Bone Fractures. XTANDI treatment may increase your risk for falls and bone fractures. Falls were not caused by loss of consciousness or seizures. Your doctor will monitor your risks for falls and bone fractures during treatment with XTANDI. Your doctor will stop treatment with XTANDI if you have serious side effects.  The most common side effects of XTANDI include: Muscle and joint pain Feeling more tired than usual Hot flashes Constipation Decreased appetite Diarrhea High blood pressure Bleeding problems Falls Bone fractures Headache XTANDI may cause fertility problems in males, which may affect the ability to father children. Talk to your doctor if you have concerns about fertility.  These are not all the possible side effects of XTANDI. For more information, talk to your doctor or pharmacist.  Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.  For further information, please talk to your doctor and click here for Patient Information and Full Prescribing Information for XTANDI.",
            "prescriptionStatus": "https://health-lifesci.schema.org/PrescriptionOnly",
            "dosageForm": "tablets",
            "administrationRoute": "oral",
            "doseSchedule": {
                "@type": "DoseSchedule",
                "frequency": "XTANDI is taken by mouth and is available in 2 dosage strengths: 40 mg and 80 mg. Take XTANDI once a day, at the same time every day, with or without food."
            },
            "offers": {
                "@type": "Offer",
                "price": "0",
                "priceCurrency": "USD",
                "url": "https://www.xtandi.com/"
            },
            "manufacturer": {
                "@type": "Organization",
                "name": "Astellas",
                "logo": "https://www.xtandi.com/img/logo-astellas.png"
            }
        }
    ]
}
/support-sign-up/
{
    "@context": "http://schema.org",
    "@type": "MedicalWebPage",
    "audience": "https://schema.org/Patient",
    "specialty": "https://schema.org/Oncologic",
    "url": "https://www.xtandi.com/support-sign-up",
    "name": "XTANDI® (enzalutamide) Support Sign Up",
    "headline": "Want to learn more about XTANDI? We're here to help",
    "description": "Sign up to receive educational resources for XTANDI® (enzalutamide). See Important Safety Information, Risks, and Benefits.",
    "potentialAction": [
        {
            "@type": "Action",
            "name": "Review FAQs",
            "description": "Frequently asked questions",
            "url": "https://www.xtandi.com/faqs"
        },
        {
            "@type": "Action",
            "name": "Watch their stories",
            "description": "Hear firsthand from men who are taking XTANDI",
            "url": "https://www.xtandi.com/patient-videos"
        },
        {
            "@type": "Action",
            "name": "Explore resources",
            "description": "Helpful XTANDI resources for patients and caregivers",
            "url": "https://www.xtandi.com/patient-resources"
        }
    ],
    "about": [
        {
            "@type": "Drug",
            "name": "XTANDI",
            "nonProprietaryName": "enzalutamide",
            "image": {
                "@type": "ImageObject",
                "name": "XTANDI® (enzalutamide) 40 mg tablets | 80 mg tablets",
                "description": "XTANDI Logo",
                "contentUrl": "https://www.xtandi.com/images/xtandi-logo.svg"
            },
            "description": "What is XTANDI? XTANDI is a prescription medicine used to treat men with prostate cancer that: no longer responds to a hormone therapy or surgical treatment to lower testosterone OR has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone OR has not spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone, and who are at high risk of cancer spreading to other parts of the body. It is not known if XTANDI is safe and effective in females or children.",
            "prescribingInfo": "https://www.astellas.us/docs/us/12A005-ENZ-WPI.pdf",
            "warning": "What should I tell my doctor before taking XTANDI? Tell your doctor about all your medical conditions, including if you:  Have a history of seizures, brain injury, stroke, or brain tumors. Have a history of heart disease, have high blood pressure, or have abnormal amounts of fat or cholesterol in your blood (dyslipidemia). Are pregnant or plan to become pregnant. XTANDI can cause harm to your unborn baby and loss of pregnancy (miscarriage). Have a partner who is pregnant or may become pregnant. Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with XTANDI and for 3 months after the last dose. Males must use a condom during sex with a pregnant female. Are breastfeeding or plan to breastfeed. It is not known if XTANDI passes into your breast milk. Take other medicines. XTANDI may affect the way other medicines work, and other medicines may affect how XTANDI works. These include prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not start or stop any medicine without talking to your doctor. How should I take XTANDI? Take XTANDI exactly as your doctor tells you. Take your prescribed dose once a day, at the same time each day. XTANDI can be taken with or without food. Swallow XTANDI capsules or tablets whole. Do not chew, dissolve, or open the capsules. Do not cut, crush or chew the tablets. Your doctor may change your dose if needed. Do not change or stop taking your prescribed dose of XTANDI without talking with your doctor first. If you are receiving gonadotropin-releasing hormone (GnRH) therapy, you should continue with this treatment while taking XTANDI unless you have had surgery to lower the amount of testosterone in your body (surgical castration). If you miss a dose of XTANDI: Take your prescribed dose as soon as you remember that day. If you miss your daily dose, take your prescribed dose at your regular time the next day. Do not take more than your prescribed dose of XTANDI each day. If you take too much XTANDI: Call your doctor or go to the nearest emergency room right away. You may have an increased risk of seizure if you take too much XTANDI. What are the possible side effects of XTANDI? XTANDI may cause serious side effects including:  Seizure. If you take XTANDI, you may be at risk of having a seizure. Avoid activities where a sudden loss of consciousness could seriously harm you or someone else. Tell your doctor right away if you lose consciousness or have a seizure. Posterior Reversible Encephalopathy Syndrome (PRES). If you take XTANDI you may be at risk of developing a condition involving the brain called PRES. Tell your doctor right away if you have a seizure or quickly worsening symptoms such as headache, decreased alertness, confusion, reduced eyesight, blurred vision or other visual problems. Your doctor will do a test to check for PRES. Allergic Reactions. Allergic reactions have happened in people who take XTANDI. Stop taking XTANDI and get medical help right away if you develop swelling of the face, tongue, lip or throat. Heart Disease. Blockage of the arteries in the heart (ischemic heart disease) that can lead to death has happened in some people during treatment with XTANDI. Your doctor will monitor you for signs and symptoms of heart problems during your treatment. Call your doctor or go to the emergency room right away if you get chest pain or discomfort at rest or with activity or shortness of breath during your treatment with XTANDI. Falls and Bone Fractures. XTANDI treatment may increase your risk for falls and bone fractures. Falls were not caused by loss of consciousness or seizures. Your doctor will monitor your risks for falls and bone fractures during treatment with XTANDI. Your doctor will stop treatment with XTANDI if you have serious side effects.  The most common side effects of XTANDI include: Muscle and joint pain Feeling more tired than usual Hot flashes Constipation Decreased appetite Diarrhea High blood pressure Bleeding problems Falls Bone fractures Headache XTANDI may cause fertility problems in males, which may affect the ability to father children. Talk to your doctor if you have concerns about fertility.  These are not all the possible side effects of XTANDI. For more information, talk to your doctor or pharmacist.  Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.  For further information, please talk to your doctor and click here for Patient Information and Full Prescribing Information for XTANDI.",
            "prescriptionStatus": "https://health-lifesci.schema.org/PrescriptionOnly",
            "dosageForm": "tablets",
            "administrationRoute": "oral",
            "doseSchedule": {
                "@type": "DoseSchedule",
                "frequency": "XTANDI is taken by mouth and is available in 2 dosage strengths: 40 mg and 80 mg. Take XTANDI once a day, at the same time every day, with or without food."
            },
            "offers": {
                "@type": "Offer",
                "price": "0",
                "priceCurrency": "USD",
                "url": "https://www.xtandi.com/"
            },
            "manufacturer": {
                "@type": "Organization",
                "name": "Astellas",
                "logo": "https://www.xtandi.com/img/logo-astellas.png"
            }
        }
    ]
}
🛡️ Trust Signals — external proof links that back the declared identity
5Review mentions (all pages)
0External proof links (all pages)
PageReviewsProof links
/ (home) 0 0
/clinical-trials/ 3 0
/talking-to-your-doctor/ 0 0
/support-sign-up/ 2 0
Explore the other reputation pillars for XTANDI (Astellas Pharma Inc.)